Irena was a home aide nurse employed to look after Charles Rodman in his home during his first bout suffering from Alzheimer's Disease. Irena had good days and bad days with Charles, noting that the day Will came home with Caesar was not so good. She also had the idea that having Caesar might be good for Charles as motivation. She quit her job after at least three years, when his behaviour became too violent in which Charles cut his hand after breaking a lamp; tearfully saying that it was no way for Charles to live before storming out. It is currently unknown if she died or survived from drug ALZ-113.
- An earlier version of the script described Irena as Russian, but she showed no evidence of a foreign accent on-screen.